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Live virus vaccines prepared by growing viruses in cell cultures are essentially devoid of potentially allergenic substances related to host tissue. Most of the widely used antigens can safely and effectively be given simultaneously. This knowledge is particularly helpful in circumstances that include imminent exposure to several infectious diseases, preparation for foreign travel, or uncertainty that the patient will return for further doses of vaccine. These include: Government Printing Office, Washington, D. The site selected should be well into the upper, outer mass of the gluteus maximus and away from the central region of the buttocks.

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Field observations indicate that simultaneous administration on the same day of the most widely used live-virus vaccines has not resulted in impaired antibody response or increased rates of adverse reactions.

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The Committee does not recommend dividing doses of any vaccine. Healthcare professionals may hesitate to use longer needles on the grounds that they are likely to cause the patient more discomfort. Advisory memoranda--Memoranda are published when necessary by CDC to advise international travelers or those who provide information to travelers about specific outbreaks of communicable diseases abroad. The Report of the Committee on Infectious Diseases of the American Academy of Pediatrics Red Book --The full report containing recommendations on all licensed vaccines is usually updated every years. In general, inactivated vaccines can be administered simultaneously at separate sites.

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